Something that is perceived to be a sure thing or very likely to happen or result in success. For Example: a boss could say to another boss, “let’s have Daniel handle the reorganizing of this department, he’s a safe bet.”

In a situation where you’re not sure which side to take, you take the side most favorable to the other party. For Example: A woman could tell her friend, “I thought my boyfriend was cheating on me, but he insisted that he wasn’t so I gave him the benefit of the doubt and stopped worrying […]

Having lost one’s sanity, particularly as a result of drug or alcohol use. For Example: “His excessive drinking is starting to send him round the bend.”

Those who are desperate are in no position to negotiate. For Example: if you gave a homeless person a candy bar and they asked for money instead, you could say, “beggars can’t be choosers!”

Disclosing some piece of information, usually a secret. For Example: If a friend was reluctant to divulge something to you, you could say, “oh c’mon, spill the beans!”