Having lost one’s sanity, particularly as a result of drug or alcohol use. For Example: “His excessive drinking is starting to send him round the bend.”

Those who are desperate are in no position to negotiate. For Example: if you gave a homeless person a candy bar and they asked for money instead, you could say, “beggars can’t be choosers!”

Disclosing some piece of information, usually a secret. For Example: If a friend was reluctant to divulge something to you, you could say, “oh c’mon, spill the beans!”

Preventing something unpleasant from coming too near to you for fear that it will harm you. For Example: If a coach was asked why he doesn’t play a particular player very often, he might say, “I’m keeping him at bay, I think it’s in the best interests of the team to do so.”

A failing activity or attempt at something. For Example: If you’re running for public office but are trailing by 30 points in the polls, you are fighting a losing battle.